User profiles for James Chong

James Chong

- Verified email at york.ac.uk - Cited by 4415

James Chong

- Verified email at sydney.edu.au - Cited by 3691

James Chong

- Verified email at csun.edu - Cited by 1086

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

JJH Chong, X Yang, CW Don, E Minami, YW Liu… - Nature, 2014 - nature.com
Pluripotent stem cells provide a potential solution to current epidemic rates of heart failure 1
by providing human cardiomyocytes to support heart regeneration 2 . Studies of human …

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin‐dependent kinases cdc2, cdk2 and cdk5

…, A Borgne, O Mulner, JPJ Chong… - European journal of …, 1997 - Wiley Online Library
Cyclin‐dependent kinases (cdk) play an essential role in the intracellular control of the cell
division cycle (cdc). These kinases and their regulators are frequently deregulated in human …

[PDF][PDF] Adult cardiac-resident MSC-like stem cells with a proepicardial origin

JJH Chong, V Chandrakanthan, M Xaymardan, NS Asli… - Cell stem cell, 2011 - cell.com
Colony-forming units – fibroblast (CFU-Fs), analogous to those giving rise to bone marrow (BM)
mesenchymal stem cells (MSCs), are present in many organs, although the relationship …

Purification of an MCM-containing complex as a component of the DNA replication licensing system

JPJ Chong, HM Mahbubani, CY Khoo, JJ Blow - Nature, 1995 - nature.com
REPLICATION licensing factor (RLF) ensures that eukaryotic chromosomal DNA is replicated
exactly once in each cell cycle 1–4 . On exit from metaphase, RLF is activated and binds to …

[HTML][HTML] Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia

…, F Yan, JJH Chong, FH Passam, BH Chong - Nature …, 2019 - nature.com
Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins,
characterized by thrombocytopenia and often severe thrombosis with high morbidity and …

A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase

JPJ Chong, MK Hayashi, MN Simon… - Proceedings of the …, 2000 - National Acad Sciences
The minichromosome maintenance (MCM) proteins are essential for DNA replication in
eukaryotes. Thus far, all eukaryotes have been shown to contain six highly related MCMs that …

[HTML][HTML] NETosis and thrombosis in vaccine-induced immune thrombotic thrombocytopenia

…, A Enjeti, SB Ting, JJH Chong, BH Chong - Nature …, 2022 - nature.com
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse
effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.COV2.S …

[PDF][PDF] Conditional correlation and volatility in commodity futures and traditional asset markets

J Chong, J Miffre - Journal of Alternative Investments, 2010 - researchgate.net
The article studies the conditional correlations between 25 commodity futures and 13 stock
and fixed-income indices. Conditional correlations with equity returns fell over time, a sign …

[PDF][PDF] Vascular cells improve functionality of human cardiac organoids

…, F Bolk, V Janbandhu, E Yao, RP Harvey, JJH Chong… - Cell Reports, 2023 - cell.com
Crosstalk between cardiac cells is critical for heart performance. Here we show that vascular
cells within human cardiac organoids (hCOs) enhance their maturation, force of contraction, …

Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart

JJH Chong, H Reinecke, M Iwata, B Torok-Storb… - 2013 - liebertpub.com
Platelet-derived growth factors (PDGFs) and their tyrosine kinase receptors play instrumental
roles in embryonic organogenesis and diseases of adult organs. In particular, platelet-…