Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort …

…, IFN Hung, Z Chen, H Chen, KY Yuen - The Lancet infectious …, 2020 - thelancet.com
Background Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial
outbreaks. Comprehensive data for serial respiratory viral load and serum antibody …

Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from a Hong Kong cohort: systematic review and meta-analysis

…, HM Cheng, AJX Zhang, KKW To, KH Chan, KY Yuen… - Gastroenterology, 2020 - Elsevier
Background & Aims Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
causes coronavirus disease 2019 (COVID-19), which has been characterized by fever…

[HTML][HTML] Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label …

…, TL Que, CS Lau, KH Chan, KKW To, KY Yuen - The Lancet, 2020 - thelancet.com
Background Effective antiviral therapy is important for tackling the coronavirus disease 2019
(COVID-19) pandemic. We assessed the efficacy and safety of combined interferon beta-1b, …

[HTML][HTML] Lung pathology of fatal severe acute respiratory syndrome

…, KW Yan, KH Chan, NC Tsang, Y Guan, KY Yuen… - The Lancet, 2003 - thelancet.com
Background Severe acute respiratory syndrome (SARS) is a novel infectious disease with
global impact. A virus from the family Coronaviridae has been identified as the cause, but the …

Imaging profile of the COVID-19 infection: radiologic findings and literature review

…, B Leung, PL Khong, CKM Hui, K Yuen… - Radiology …, 2020 - pubs.rsna.org
Purpose To present the findings of 21 coronavirus disease 2019 (COVID-19) cases from two
Chinese centers with CT and chest radiographic findings, as well as follow-up imaging in …

Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-PCR assay validated in …

…, KH Chan, OTY Tsang, KY Yuen - Journal of clinical …, 2020 - Am Soc Microbiol
On 31 December 2019, the World Health Organization was informed of a cluster of cases of
pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified a …

[PDF][PDF] COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing

…, KH Kok, VC Cheng, KY Yuen - Clin …, 2020 - dubito.s3.eu-central-1.amazonaws …
Kwok-Yung Yuen Email: kyyuen@ hku. hk Phone number:(852)-22552413 Carol Yu Centre
for Infection, State Key Laboratory of Emerging Infectious Diseases, Department of …

Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis

…, W Luk, SF Sia, MHS Wu, KH Chan, KY Yuen… - Journal of …, 2005 - Am Soc Microbiol
The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear. Macrophages
are key sentinel cells in the respiratory system, and it is therefore relevant to compare …

Coronavirus disease 2019 (COVID-19) re-infection by a phylogenetically distinct severe acute respiratory syndrome coronavirus 2 strain confirmed by whole genome …

…, KH Kok, VCC Cheng, KY Yuen - Clinical Infectious …, 2021 - academic.oup.com
Background Waning immunity occurs in patients who have recovered from Coronavirus
Disease 2019 (COVID-19). However, it remains unclear whether true re-infection occurs. …

[HTML][HTML] Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3· TANK· TBK1/IKKϵ complex

KL Siu, KH Kok, MHJ Ng, VKM Poon, KY Yuen… - Journal of Biological …, 2009 - ASBMB
Severe acute respiratory syndrome (SARS) coronavirus is highly pathogenic in humans and
evades innate immunity at multiple levels. It has evolved various strategies to counteract the …