Adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) is a key player in
regulating energy metabolism, placing it at the center stage in studies of diabetes and related …

Leptin is the protein product encoded by the obese (ob) gene. It is a circulating hormone
produced primarily by the adipose tissue. ob/ob mice with mutations of the gene encoding leptin …

… We also thank Li-qiang Wang, Wei-peng Cai and Zi-sheng Chen (Sixth Affiliated Hospital of
Guangzhou Medical University), Chang-xing Ou, Xiao-min Peng, Si-ni Cui, Yuan Wang, Mou …

Nanogel-based nanoplatforms have become a tremendously promising system of drug
delivery. Nanogels constructed by chemical crosslinking or physical self-assembly exhibit the …

Sulfate aerosols exert profound impacts on human and ecosystem health, weather, and
climate, but their formation mechanism remains uncertain. Atmospheric models consistently …

To better determine the history of modern birds, we performed a genome-scale phylogenetic
analysis of 48 species representing all orders of Neoaves using phylogenomic methods …

Mice carrying a mutation in the synaptotagmin I gene were generated by homologous
recombination. Mutant mice are phenotypically normal as heterozygotes, but die within 48 hrafter …

Homoskedasticity is an important assumption in ordinary least squares (OLS) regression.
Although the estimator of the regression parameters in OLS regression is unbiased when the …

Here we describe the comprehensive gene expression profiles of each cell type composing
normal breast tissue and in situ and invasive breast carcinomas using serial analysis of …

High-quality data are the precondition for analyzing and using big data and for guaranteeing
the value of the data. Currently, comprehensive analysis and research of quality standards …